I've been diving a bit into the RAM configuration of our new R710 Dell servers. They have new memory configuration settings. "Memory Optimized" mode can yield a 50% performance improvement at no cost other than to place DIMMs in appropriate slots. Dell has a white paper detailing the options a bit more: Optimizing DDR3 Memory Settings in New 11th-Generation Dell PowerEdge Servers. It also lists trade-offs of choosing one configuration over the other or when to go for a balanced intermediate.